منابع مشابه
The Role of Toll-Like Receptors in Breast Cancer
Breast cancer is highly prevalent worldwide. Treatment of this disease is a major global public health problem; therefore, numerous studies have explored new molecular profile helping for breast cancer therapy. Different risk factors are attributed to breast cancer; however, chronic inflammation and immune regulation are highly essential. Various molecules impact this context, including toll-li...
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Background: Endometriosis is a complex disease that profoundly affects the quality of life in many women. This disease affects roughly one in ten women of reproductive age. Endometriosis induces a variable amount of inflammatory reaction in pelvic environment. An active immune system needs to recognize these inflammatory agents. Rapid innate immune system defenses against infections involve the...
متن کاملToll-Like Receptors: Role in Dermatological Disease
Toll-like receptors (TLRs) are a class of conserved receptors that recognize pathogen-associated molecular patterns (PAMPs) present in microbes. In humans, at least ten TLRs have been identified, and their recognition targets range from bacterial endotoxins to lipopeptides, DNA, dsRNA, ssRNA, fungal products, and several host factors. Of dermatological interest, these receptors are expressed on...
متن کاملToll-like receptors and chronic lung disease.
TLRs (Toll-like receptors) comprise a family of proteins whose function is principally to facilitate the detection of, and response to, pathogens. Protozoa, helminths, viruses, bacteria and fungi can all activate TLR signalling, and these signals have important roles in the activation of host defence. TLRs may also respond to products of tissue damage, providing them with roles in infective and...
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ژورنال
عنوان ژورنال: Current Opinion in Nephrology and Hypertension
سال: 2009
ISSN: 1062-4821
DOI: 10.1097/mnh.0b013e32832a1d5f